The diagnosis of Malaria is done by use of clinical signs and laboratory techniques. Physical examinations show a patient exhibiting signs like weakness, perspiration, elevated temperatures, enlargement of the liver and the spleen and increased respiratory rate.

Diagnosis by laboratory techniques requires that a blood sample be taken from a patient and the specimen studied under a microscope to reveal the parasites in the blood. The lab study can also show the decreased number of blood cells in the blood, which is clinically manifested as anemia. Apart from blood, saliva and urine can also be used for the lab test, although a blood sample is most preferred and dependable.

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